Morphological characteristics and correlation of chronic hematogenous osteomyelitis with latent clinical course (Garre type)

Authors

  • Valeriy Hryhorovskyi
  • Mykola Hrytsai
  • Andrew Hordii
  • Olga Lyutko
  • Anastasiya Hryhorovska

DOI:

https://doi.org/10.15674/0030-5987201715-13

Keywords:

sclerosing hematogenous os¬teomyelitis, pathohistological features, morphological indices, correlation analysis

Abstract

One of the clinico-morphological variants of osteomyelitis with latent course is sclerosing hematogenous osteomyelitis of the Garre type.

Objective: on the basis of pathomorphological and gradation-morphometric studies of bone lesion, establish statistical differences between individual forms and correlation links between the morphological indices of lesions of the bone of patients with sclerosing hematogenous osteomyelitis.

Methods: fragments of affected bones of 25 patients with clinically es­tablished sclerosing hematogenous osteomyelitis were studied. On the basis of pathohistological study, morphological indi­ces were identified, with the use of which gradation-frequency and correlation analysis of nonparametric data was carried out with the calculation of the association coefficient.

Results: despite the general similarity of morphological manifestations, differences in the forms of sclerosing hematogenous osteo­myelitis were established: about ⅔ of all cases corresponded to the fibrosing form of the focus without the presence of exuda­tive inflammation. In the remaining cases, in addition to fibrosis and osteosclerosis, the foci of osteomyelitis contained microab­scesses, within which small sequestrations were found. Forms of foci of sclerosing hematogenous osteomyelitis can eventu­ally move from one to another. Between the fibrotic with micro-abscess formation of sclerosing hematogenous osteomyelitis and the presence of microsequesters in the microabscesses, a re­liable positive correlation was found between the mean force (ra= +0.620). Sequesters in tissues were not observed in the foci of fibrosis.

Conclusions: sclerosing hematogenous osteomyelitis is a clinical variant with a latent course mainly in adolescent patients, in which there is no macrodefective damage to the bone marrow and bone tissue by an infectious inflammatory process, namely: large abscesses, significant sequestration, parasseous abscesses and fistulas.

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How to Cite

Hryhorovskyi, V., Hrytsai, M., Hordii, A., Lyutko, O., & Hryhorovska, A. (2017). Morphological characteristics and correlation of chronic hematogenous osteomyelitis with latent clinical course (Garre type). ORTHOPAEDICS TRAUMATOLOGY and PROSTHETICS, (1), 5–13. https://doi.org/10.15674/0030-5987201715-13

Issue

No. 1 (2017)

Section

ORIGINAL ARTICLES

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Copyright (c) 2017 Valeriy Hryhorovskyi, Mykola Hrytsai, Andrew Hordii, Olga Lyutko, Anastasiya Hryhorovska

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