Age features of mineral density and quality of bone tissue in men

Vladyslav Povorozniuk, Anna Mysiienko, Nataliya Dzerovych

Abstract


Objective: To evaluate the quality score (TBS) and bone mineral density (BMD) in practically healthy Ukrainian men.

Methods: There were examined 191 healthy men aged from 30 to 89 years (average age 57,4 ± 13,7, average growth (174,4 ± 6,8) cm, and average body weight 76.6 ± 9,3 kg). Depending on the age all surveyed men were divided into six groups by decades: 30–39 (19 persons), 40–49 (34), 50–59 (48), 60–69 (48), 70–79 (34), 80–89 (8). By means of dual energy X-ray densitometry method («Prodigy, GE Lunar», Madison, USA) we measured BTMD at the lumbar spine (LI-LIV) level, femoral neck, entire skeleton and ultradistal part of the forearm. Indicator TBS for the lumbar spine we deter­mined using the procedure TBS iNsight («Med-Imaps», Pessac, France).

Results: significant decline of TBS LI–LIV begins in men since 60 years and amount 1,152 ± 0,18 vs 1,263 ± 0,12 in men 30–39 years of age group (p = 0,01), and 1,273 ± 0, 12 in group of 40–49 years (p <0,001). Also in men we have identified decreasing with age BMD of the femoral neck (F = 5,38; p <0,001), the entire skeleton (F = 7,75; p < 0,001) and ultradistal part of forearm bones (F = 3,34; p = 0.007). Reliable correlation TBS index with age was found (r = –0,25; p = 0,0007). However the relationship between TBS and BMD indeces on the lumbar spine and femoral neck was not revealed.

Conclusions: age has a significant impact on the variability of TBS index and its structural and functional state. According to results of dual energy X-ray absorptiometry reliable decreasing of BMD in men with age one may observe at the level of the femoral neck, entire skeleton and bones of the forearm.


Keywords


quality of trabecular bone tissue; bone mineral density; men

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DOI: https://doi.org/10.15674/0030-59872015365-70

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