Frequency differences and correlation dependences of morphological indices of the state of tissues in aneurismal osteocystomata
DOI:
https://doi.org/10.15674/0030-59872012359-70Keywords:
aneurismal bone cysts, histological peculiarities of focus tissues, morphological characteristics of tissue state, analysis of frequencies, correlation dependencesAbstract
The purpose of the present research was as follows: on the basis of an analysis of biopsic-histological material, to reveal peculiarities of morphological changes, which are observed in lesion foci in cases of primary and recurrent aneurismal bone cysts (ABC), to determine differences in frequency of pathological changes with different intensity and correlation dependences between separate morphological indices in comparison groups. Tissues of 94 resectates from bone lesion foci of sick children and adolescents served as the material for this study. It was found out that ABC was a tumour-like osteodestructive lesion with a cyclic course, characterized by persisting blood disturbances, a high resorptive-proliferative activity, dystrophic changes as well as pathological (atypical) and reparative osteogenesis in the tissue of capsular-septal structures. As a result of the conducted clinical-morphological study, different frequencies of cases with different intensity of morphological indices in ABC comparison groups and subgroups were revealed: primary – recurrent, non-juxtaphyseal – juxtaphyseal, and the cysts which did or did not recur later after their surgical treatment. Correlation dependencies between separate morphological indices were detected, with determination of the parameters, sign and reliability of association factor values.
References
- «Солидный» вариант аневризмальной кисты кости / А. П. Бережный, В. Н. Бурдыгин, А. И. Снетков, Г. Н. Берченко и др. // Вестн. травматол. и ортопедии им. Н. Н. Приорова. — 1999. — № 1. — С. 38–45.
- Остеобластокластома у детей и подростков / М. В. Волков, Г. И. Лаврищева, А. В. Баева, А. П. Бережной // Ортопед. травматол. — 1985. — № 10. — С. 9–13.
- Григоровский В. В. Аспекты клинической патологии, морфологической дифференциальной диагностики и патогенеза аневризмальных костных кист / В. В. Григоровский // Ортопед. травматол. — 1999. — № 3. — С. 122–127.
- Григоровський В. В. Номенклатура, гістологічні особливості та диференціальна діагностика гігантоклітинних проліферативних уражень кісток у дітей та підлітків / В. В. Григоровський // Онкология. — 2002. — № 3. — С. 174–183.
- Рецидиви аневризмальних кіст кісток у дітей та підлітків: можливі причини та нез’ясовані теоретичні питання / А. П. Крись-Пугач, Ю. М. Гук, В. В. Григоровський, А. В. Рославцев // Вісник ортопедії, травматології та протезування. — 2011. — № 1. — С. 5–10.
- Семенова Л.А. Морфологические особенности аневризмальных кист костей: автореф. дис… на соискание ученой степени канд. мед. наук: 14.00.15 / Л. А. Семенова — М., 2002. — 25 с.
- Solid Variant of Aneurysmal Bone Cyst / F. Bertoni, P. Bacchini, R. Capanna, P. Ruggieri // Cancer. — 1993. — Vol. 71, № 3. — P. 729–734.
- Juxtaepiphyseal Aneurysmal Bone Cyst / R. Capanna, D. S. Springfield, R. Biagini et al. // Skeletal Radiol. — 1985. — Vol. 13, № 1. — P. 21–25.
- Cottalorda J. Modern concepts of primary aneurysmal bone cyst / J. Cottalorda, S. Bourelle // Arch. Orthop. Trauma Surg. — 2007. — Vol. 127. — P. 105–114.
- De Silva M. V. C. Fibromyxoid areas and immature osteoid are associated with recurrence of primary aneurysmal bone cysts / M. V. C. De Silva, N. Raby, R. Reid // Histopathology. — 2003. — Vol. 43. — P. 180–188.
- Aneurysmal bone cysts in young children / A. A. Freiberg, R. T. Loder, K. P. Heidelberger, R. N. Heusinger // J. Pediatr. Orthop. — 1994. — Vol. 14, № 1. — P. 86–91.
- Ilaslan H. Solid variant of aneurysmal bone cysts in long tubular bones: giant cell reparative granuloma / H. Ilaslan, M. Sundaram, K. K. Unni // Am. J. Roentgenol. — 2003. — Vol. 180, № 6. — P. 1681–1687.
- Aneurysmal bone cyst of the paediatric shoulder girdle: A case series and literature review / R. Kaila, M. Ropars, W. Briggs et al. // J. Pediaric Orthop. — 2007. — Vol. 16. — P. 429–436.
- Aneurysmal Bone Cysts Recur at Juxtaphyseal Locations in Skeletally Immature Patients / P. P. Lin, Ch. Brown, A. K. Raymord et al. // Clin. Orthop. Rel. Res. — 2008. — V. 466, № 3. — P. 722–728.
- Aneurysmal bone cyst: A Review of 150 Patients / H. J. Mankin, F. J. Hornicek, E. Ortiz-Cruz et al // J. Clin. Oncol. — 2005. — Vol. 23, № 27. — P. 6756–6762.
- Rosenberg A. E. Aneurysmal bone cyst / A. E. Rosenberg, G. P. Nielsen, J. A. Fletcher // Pathology and genetics of tumours of soft tissue and bone. WHO classification of tumours / Ed. C. D. M. Fletcher, K. K. Unni, F. Mertens. — Lyon: IARC Press, 2002. — P. 338–339.
- Aneurysmal bone cyst: Its pathogenesis based on angiographic, immunohistochemical and electron microscopic studies / M. Szendröi, G. Arató, A. Ezzati et al. // Pathol. Oncol. Res. — 1998. — Vol. 4, № 4. — P. 277–281.
- Aneurysmal bone cyst: A clinicopathologic study of 238 cases / A. M. Vergel de Dios, J. R. Bond, T. C. Shives et al. // Cancer. — 1992. — Vol. 69. — P. 2921–2931.
- Biologic characterization of human bone tumors. VI. The aneurysmal bone cyst: an enzyme histochemical, electron microscopical, and immunohistological study / E. Vollmer, A. Roessner, K. H. Lipecki et al. // Virchows Arch. — 1987. — Vol. 53, № 1. — P. 58–65.
Downloads
How to Cite
Issue
Section
License
Copyright (c) 2014 Valeriy Hryhorovsky, Yuriy Guk, Andrey Roslavtsev
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors retain the right of authorship of their manuscript and pass the journal the right of the first publication of this article, which automatically become available from the date of publication under the terms of Creative Commons Attribution License, which allows others to freely distribute the published manuscript with mandatory linking to authors of the original research and the first publication of this one in this journal.
Authors have the right to enter into a separate supplemental agreement on the additional non-exclusive distribution of manuscript in the form in which it was published by the journal (i.e. to put work in electronic storage of an institution or publish as a part of the book) while maintaining the reference to the first publication of the manuscript in this journal.
The editorial policy of the journal allows authors and encourages manuscript accommodation online (i.e. in storage of an institution or on the personal websites) as before submission of the manuscript to the editorial office, and during its editorial processing because it contributes to productive scientific discussion and positively affects the efficiency and dynamics of the published manuscript citation (see The Effect of Open Access).