Microbiological and serological indices in patients with aseptic instability of elements of a hip joint endoprosthesis and their diagnostic assessment

Authors

  • Svitlana Bidnenko
  • Olga Lyutko
  • Lyudmyla Riabokon
  • Katerina Vitrak
  • Olexiy Sulima

DOI:

https://doi.org/10.15674/0030-59872011356-59

Keywords:

aseptic instability of endoprosthesis, microflora of periprosthetic tissues, antibiotic susceptibility, diagnostic criterions

Abstract

The article deals with detection of the rate and species composition of causative agents of a latent infection or contamination of periprosthetic tissues of the hip joint with revealing of their antibiotic sensitivity. Microorganisms were found in 43.5% of patients in cultures and in 65.2% of cases by means of microscopes. Microflora was presented by Gram-positive microorganisms: coagulase-negative staphylococci, including those with SCVs phenotype, catalase-negative cocci of Gemella spp. genus, coryneforms, which were identical in different samples from the same patient. A high individually different sensitivity to antibiotics and a high resistance of the revealed species of microorganisms to methicillin are shown. The information value of patients’ blood serum as to dynamics and level of antibodies to the revealed cultures was assessed. Such concepts as «infection» and «contamination» of tissues around the unstable component of the endoprosthesis were clearly differentiated depending upon the intensity of indices.

References

  1. Сучасні аспекти етіологічної діагностики парапротезної інфекції після ендопротезування кульшового та колінного суглобів / С.І. Бідненко, М.П. Грицай, О.Б. Лютко та ін. // Вісн. ортопед., травматол. та протез. — 2008. — № 1(56). — С. 22–27.
  2. Хирургическое лечение деформирующего артроза тазобедренного сустава воспалительной природы / В.В. Маловичко, Е.В. Огарев, З.И. Уразгильдеев и др. // Вестн. травматол. и ортопед. им. Н.И. Приорова. — 2008. — № 4. — С. 32–40.
  3. Науменко З.С. Характеристика микрофлоры у больныхс заболеваниями крупных суставов / З.С. Науменко, Е.А. Волокитина, И.В. Годовых // Гений ортопедии. — 2008. — № 3. — С. 32–34.
  4. Ревизионное эндопротезирование при асептической нестабильности вертлужной компонента / Г.М. Кронтор, М.И. Дарчук, О.П. Пулбере и др. // Ортопед. травматол. — 2008. — № 4. — С. 67–70.
  5. Ефективність діагностичних дисків з батуміном при індикації стафілококів / В.В. Смирнов, Л.М. Чуркіна, Г.А. Носенко, С.І. Бідненко // Лікарська справа. — 2002. — № 5–6. — С. 27–31.
  6. Шерепо Н.К. Асептическая нестабильность протеза как основная проблема тотального эндопротезирования тазобедренного сустава: пути решения / Н.К. Шерепо, К.М. Шерепо // Вестн. травматол. и ортопед. им. Н.Н. Приорова. — 2007. — № 1. — С. 43–47.
  7. Cameron H.U. The effect of early infection on bone ingrowth into porous metal implants / H.U. Cameron, B.T. Yoneda, R.M. Pillar // Acta Orthopoed. Belg. — 1977. — Vol. 43. — P. 71–74.
  8. Fuerst M. The value of preoperative knee aspiration and arthroscopic biopsy in revision total knee arthroplasty / M. Fuerst, B. Fink, W. Ruther // J. Orthop. Ihre Grenzgeb. — 2005. — Vol. 143 (1). — P. 36–41.
  9. Extra-abdominal infections due to Gemella species / J.M. Garsia-Lechuz, O. Cuevas-Lobato, S. Hemamgomez et al. // Int. J. Infect. Dis. — 2002. — Vol. 6. — P. 78–82.
  10. Evaluation of measures to decrease intra-operative bacterial contamination in orthopaedic implant surgery / B.A. Knobben, J.K. Van Horn, H.C. Vander Mej, H.J. Busscher // J. Hosp. Infect. — 2006. — Vol. 62. — P. 174–180.
  11. McNamara P.J. Staphylococcus aureus small colony variants, electron transport and persistent infections / P.J. McNamara, R.A. Proctor // Intern. J. Antimicrobial Agents. — 2000. — № 14. — P. 117–122.
  12. Musil D. Our experience with revision total knee arthroplasty / D. Musil, J. Stehlik, M. Starek // Acta Chir. Orthop. Traumatol. Cech. — 2005. — Vol. 72. — P. 6–15.
  13. Staphylococcal Small Colony Variants Have Novel Mechanisms for Antibiotic Resistance / R.A. Proctor, B. Kahl, V.Ch. Eiff, P.E. Vaudaux // Clin. Infect. Dis. — 1998. — Vol. 27 (Suppl 1). — P. 568–574.
  14. Szczesny G. Septic loosing of hip and knee prosthesis / G. Szczesny, J. Babiak, M. Kowalewski // Chir. Nazzadow Ruchu Ortop. Pol. — 2005. — Vol. 70. — P. 179–184.

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How to Cite

Bidnenko, S., Lyutko, O., Riabokon, L., Vitrak, K., & Sulima, O. (2011). Microbiological and serological indices in patients with aseptic instability of elements of a hip joint endoprosthesis and their diagnostic assessment. ORTHOPAEDICS TRAUMATOLOGY and PROSTHETICS, (3), 56–59. https://doi.org/10.15674/0030-59872011356-59

Issue

No. 3 (2011)

Section

ORIGINAL ARTICLES

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Copyright (c) 2014 Svitlana Bidnenko, Olga Liutko, Lyudmyla Riabokon, Katerina Vitrak, Olexiy Sulima

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