Peculiarities in clinical and pathomorphological manifestations of osteoarthrosis of their lower extremities in patients with spondyloepiphyseal dysplasia

Authors

DOI:

https://doi.org/10.15674/0030-5987201139-13

Keywords:

osteoarthrosis, spondyloepiphyseal dysplasia, glycosaminoglycans, collagen

Abstract

The study involved 133 patients with stages 2–4 of osteoarthrosis of knee and hip joints, which developed against a background of spondyloepiphyseal dysplasia. It was revealed that changes in the locomotor system and veins of the lower extremities were the basic clinical manifestations of the syndrome of connective tissue dysplasia. Forty-five patients, who underwent total arthroplasty of their hip and knee joints, had densitometry, thermography and an immunological blood examination before the operation; after the surgical intervention, the regenerative potential of marrow stromal stem cells in the epiphyses of the femoral and tibial bones was studied by cloning the above cells in vitro and the articular cartilage was histologically examined. The revealed changes, including a threat of a decreased potential of the osseous tissue remodelling, give grounds to extend indications for arthroplasty in the above category of patients.

References

  1. Альхайдар Х.М. Тотальное эндопротезирование тазобедренного сустава при коксартрозе III–IV стадии эндопротезом с металло-металлической парой трения у лиц молодого возраста: дис. ... канд. мед. наук: 14.00.22 / Альхайдар Хассан Мухаммад. — М., 2008. — 103 с.
  2. Арабидзе Г.Г. Остеоартрозы / Г.Г. Арабидзе, С.В. Желваков // Терапевт. — 2010. — № 6. — С. 60–65.
  3. Артеменко Н.А. Особенности прогрессирования и лечения остеоартроза / Н.А. Артеменко, М.А. Чвамания // Русский мед. журнал. — 2005. — Т. 13, № 7. — С. 403–406.
  4. Астахова В.С. Остеогенные клетки-предшественники костного мозга человека / В.С. Астахова. — К.: «Феникс», 2000. — 176 с.
  5. Бадокин В.В. Пути оптимизации терапии остеоартроза / В.В. Бадокин // РМЖ. — 2006. — Т. 14, № 5. — С. 1824–1828.
  6. Гайко Г.В. Сучасні підходи до профілактики та лікування остеоартрозу / Г.В. Гайко, А.Т. Бруско // Літопис травматології та ортопедії. — 2008. — № 1–2. — С. 157–160.
  7. Ерохин П.А. Тотальное эндопротезирование тазобедренного сустава при постостеотомических деформациях проксимального отдела бедренной кости: автореф. дис. … канд. мед. наук: 14.01.15 / П.А. Ерохин. — М., 2010. — 26 с.
  8. Кадурина Т.И. Дисплазия соединительной ткани. Руководство для врачей / Т.И. Кадурина, В.Н. Горбунова. — СПб.: ЭЛБИ, 2009. — 714 с.
  9. Профілактика ускладнень і помилок при ендопротезуванні кульшового суглоба / М.О. Корж, В.А. Філіпенко, В.О. Танькут, О.В. Танькут // Травма. — 2006. — № 3. — С. 390–393.
  10. Корж Н.А. Остеоартроз: консервативная терапия / Н.А. Корж, Н.В. Дедух, И.А. Зупанец и др. — Харьков: Золотые страницы, 2007. — 424 с.
  11. Constantine V.S. Selective staining of human dermal collagen II. The use of picrosirius red F3BA with polarization microscopy / V.S. Constantine, R.W. Mowry // J. Invest. Dermatol. — 1968. — Vol. 968, № 50. — Р. 419–423.
  12. Martel-Pelletier J. Effects of chondroitin sulfate in the pathophysiology of the osteoarthritic joint: a narrative review / J. Martel-Pelletier, T.S. Kwan, J.P. Pelletier // Osteoarthritis Cartilage. — 2010. — № 18, Supp l. 1. — Р. 7–11.
  13. Moskowitz R.W. Osteoarthritis: diagnosis and medical; surgical management / R.W. Moskowitz, R.D. Altman, M.C. Hochberg. — Philadelphia: Lipp pp incott Williams&Wilkins, 2006. — 470 p .
  14. Meta-analysis: chondroitin for osteoarthritis of the knee or hip / S. Reichenbach, R. Sterchi, M. Scherer et al. // Ann. Intern. Med. — 2007. — Vol. 146, № 8. — P. 580–590.
  15. Patient characteristics affecting the prognosis of total hip and knee joint arthroplasty: a systematic review / P.L. Santaguida, G.A. Hawker, P.L. Hudak et al. // J. Can. Chir. — 2008. — Vol. 51, № 6. — P. 428–436.
  16. Wilson J.F. To stop osteoarthritis, fixing cartilage may not be enough / J.F. Wilson // Ann. Intern. Med. — 2007. — Vol. 147, № 6. — P. 437–439.

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How to Cite

Guzhevsky, I., Gerasimenko, S., Dedukh, N., & Panchenko, O. (2011). Peculiarities in clinical and pathomorphological manifestations of osteoarthrosis of their lower extremities in patients with spondyloepiphyseal dysplasia. ORTHOPAEDICS TRAUMATOLOGY and PROSTHETICS, (3), 9–13. https://doi.org/10.15674/0030-5987201139-13

Issue

No. 3 (2011)

Section

ORIGINAL ARTICLES

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Copyright (c) 2014 Igor Guzhevsky, Sergey Gerasimenko, Ninel Diedukh, Olesya Panchenko

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