Methods for modelling femoral diaphysial deformities in rats
DOI:
https://doi.org/10.15674/0030-59872010176-79Keywords:
diaphysial deformities, modelling, femur, ratsAbstract
The purpose of the present work was to create experimental models of posttraumatic femoral diaphysial deformities in laboratory rats. The authors developed and described models with use of intraosseal (stable and unstable osteosynthesis) and external pin-rod (stable osteosynthesis) fixing devices in detail. The developed experimental models can be used for studying structural-functional changes in injured segments in presence of posttraumatic diaphysial deformities.References
- Weight M. Early results of the less invasive stabilization system for mechanically unstable fractures of the distal femur (AO/OTA types A2, A3, C2, and C3) [Text] / M. Weight, C. Collinge // J. Orthop. Trauma. — 2004. — Vol. 18. — P. 503–508.
- Шевцов В. И. Лечение ложных суставов трубчатых ко¬стей методом управляемого чрескостного остеосинтеза [Текст] / В. И. Шевцов // Гений ортопедии. — 1996. — № 4. — С. 30–34.
- Романенко К. К. Діафізарні переломи довгих кісток, що не зрослися (чинники ризику, діагностика, лікування) [Текст]: автореф. дис. канд. мед. наук: 14.01.21 / Костянтин Костянтинович Романенко. — Харків, 2002. — 19 с.
- Allogenic mesenchymal cells regenerate bone in a critical-sized canine segmental defect [Text] / T. L. Arinzen, S. J. Peter, M. P. Archambault et al. // J. Bone Join Surg. — 2003. — Vol. 85-A. — P. 1927–1935.
- Saito T. Osteogenic response of hydroxyapatite cement implanted into the femur of rats with experimentally induced osteoporosis [Text] / T. Saito, Y. Kin, T. Koshino // Biomateriаls. — 2002. — Vol. 23. — P. 2711–2716.
- Recombinant human platelet-derived growth factor-BB augmentation of new-bone formation in a rat model of distraction osteogenesis [Text] / D. C. Moore, M. G. Ehrlich, S. C. McAllister et al.// J. Bone Joint Surg. — 2009. — Vol. 91-A. — P. 1973–1984.
- Scianidi M. F. Evaluation of recombinant human bone morphogenetic protein-2 as a bone graft substitute in a canine segmental defect model [Text] / M. F. Scianidi, K. D. Johnson // J. Orthoh. Res. — 2000. — Vol. 18. — P. 289–302.
- Tissues formed during distraction osteogenesis in the rabbit are determined by the distraction rate: Localization of the cells that express the mRNAs and the distribution of types I and II collagens [Text] / G. Li, A. S. Virdi, D. E. Ashhurst et al. // Cell Biol. Int. — 2000. — Vol. 24. — P. 25–33.
- Fracture healing a mouse model for senile osteoporosis [Text] / M. Egermann, P. Heil, I. Groengroeft et al. // European Cell and Mat. — 2007. — Vol. 14, Suppl. 1. — P. 4.
- Корж А. А. Репаративная регенерация кости [Текст] / А. А. Корж, А. М. Белоус, Е. Я. Панков. — М.: Медицина, 1972. — 270 с.
- Корж Н. А. Репаративная регенерация кости: современный взгляд на проблему. Стадии регенерации/ Н. А. Корж, Н. В. Дедух // Ортопед. травматол. — 2006. — № 1. — Р. 77–84.
- Малышкина С. В. Экспериментальное моделирование в научных исследованиях Института патологии позвоночника и суставов им. проф. М. И. Ситенко / С. В. Малышкина // Ортопед. травматол. — 2007. — №4. — С. 5–16.
- Пат. UA 39329 U, А61B 17/00, G09B 23/00. Спосіб моделювання перелому трубчатих кісток у дослідних тварин / Романенко К. К., Горидова Л. Д., Паздніков Р. В., Прозоровський Д.В.; заявник і патентовласник ДУ «Інститут патології хребта та суглобів ім. проф. М. І. Ситенка АМН України». — № u200810277; заявл. 11.08.2008; опубл. 25.02.2009, Бюл. №4.
Downloads
How to Cite
Issue
Section
License
Copyright (c) 2014 Mykola Korzh, Konstantin Romanenko, Natalya Ashukina
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors retain the right of authorship of their manuscript and pass the journal the right of the first publication of this article, which automatically become available from the date of publication under the terms of Creative Commons Attribution License, which allows others to freely distribute the published manuscript with mandatory linking to authors of the original research and the first publication of this one in this journal.
Authors have the right to enter into a separate supplemental agreement on the additional non-exclusive distribution of manuscript in the form in which it was published by the journal (i.e. to put work in electronic storage of an institution or publish as a part of the book) while maintaining the reference to the first publication of the manuscript in this journal.
The editorial policy of the journal allows authors and encourages manuscript accommodation online (i.e. in storage of an institution or on the personal websites) as before submission of the manuscript to the editorial office, and during its editorial processing because it contributes to productive scientific discussion and positively affects the efficiency and dynamics of the published manuscript citation (see The Effect of Open Access).