The morphological state of the knee joint tissue of rats in a modelled endoprosthetics of the tibia
DOI:
https://doi.org/10.15674/0030-59872009370-75Keywords:
growing rats, knee joint, arthroplasty, histologyAbstract
The article deals with the results of a histological examination of the knee joint tissues after an experimental modelling of endoprosthetics in the proximal tibial epiphysis of laboratory rats with an uncompleted growth. It was found out that a unipolar endoprosthetics caused structural disturbances of the articular cartilage in the adjacent (not operated) femoral bone with the retained structure and height of the epiphysial cartilage. Animals of the control group (an injure of the epimetaphysis without any prosthetics) developed an osteochondrous adhesion in the knee joint, the defect area was filled with some fibrillar connective and fibroreticular tissues, the femur revealed pronounced destructive changes in the articular and epiphysial cartilages. The height of their epiphysial cartilage in the controls was reliably less versus the animals from the experimental and intact groups.
References
- Автандилов Г.Г. Медицинская морфометрия / Г.Г. Автан-дилов. — М.: Медицина, 1990. — C. 384.
- Васылык Г.Г. О влиянии росткового хряща на рост трубчатых костей в длину / Г.Г. Васылык // Ортопед., травматол. — 1971. — № 5. — С. 24–27.
- Вплив ушкодження епіфіза та наросткової пластинки кістки на подальший ріст кінцівки після ендопротезування (експериментальне дослідження) / С.Д. Шевченко, В.В. Баєв, С.В. Малишкіна, О.А. Нікольченко // Ортопед., травматол. — 2008. — №4. — С. 62–66.
- Європейська конвенція про захист хребетних тварин, що використовуються для дослідних та інших наукових цілей. Страсбург, 18 березня 1986 року: офіційний переклад [Електронний ресурс] / Верховна Рада України. — Офіц. веб-сайт. — (Міжнародний документ Ради Європи). — Режим доступу до документа: http://zakon.rada.gov.ua/cgi-bin/laws/main.cgi?nreg=994_137
- Житников А.Я. Зона пролиферации эпифизарного хряща костей конечностей животных с разными темпами и продолжительностью роста // Вісник ортопед., травматол. та протез. — 2007. — № 3. — С. 69–72.
- Зайченко И.Л. Влияние разных повреждений эпифизарного хряща на рост костей / И.Л. Зайченко // Ортопедия и травматология. — 1940. — № 2. — С. 62–68.
- Микроскопическая техника: Руководство / Под ред. Д.С. Саркисова, Ю.Л. Перова. — М.: Медицина, 1996. — 544 с.
- Протезирование детей с дефектами конечностей / Под ред. В.И. Филатова. — Л.: Медгиз, 1981. — 280 с.
- Campbell C.J. The effects produced in the cartilaginous epiphyseal plate of immature dogs by experimental surgical traumata / C.J. Campbell, A. Grisolia, G. Zanconato // J. Bone Joint Surg. — 1959. — Vol. 41-A, № 7. — P. 1221–1242.
- Key J.A. A study of experimental trauma to the distal femoral epiphysis in rabbits / J.A.Key, L.T.Ford // J. Bone Joint Surg. — 1958. — Vol. 40-A, № 4. — P. 887–896.
- Morphometric changes in the epiphyseal plate of the growing and young adult male rat after long-term salmon calcitonin administration / L. Khaldi, T. Karachalios, A. Galanos, G.P. Lyritis // Calcif. Tissue Inter. — 2005. — Vol. 76, № 6. — P. 426–432.
Downloads
How to Cite
Issue
Section
License
Copyright (c) 2014 Svitlana Malyshkina, Olga Nikolchenko, Stanislav Shevchenko, Vitaliy Baev
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors retain the right of authorship of their manuscript and pass the journal the right of the first publication of this article, which automatically become available from the date of publication under the terms of Creative Commons Attribution License, which allows others to freely distribute the published manuscript with mandatory linking to authors of the original research and the first publication of this one in this journal.
Authors have the right to enter into a separate supplemental agreement on the additional non-exclusive distribution of manuscript in the form in which it was published by the journal (i.e. to put work in electronic storage of an institution or publish as a part of the book) while maintaining the reference to the first publication of the manuscript in this journal.
The editorial policy of the journal allows authors and encourages manuscript accommodation online (i.e. in storage of an institution or on the personal websites) as before submission of the manuscript to the editorial office, and during its editorial processing because it contributes to productive scientific discussion and positively affects the efficiency and dynamics of the published manuscript citation (see The Effect of Open Access).