Influence of low temperatures and ethanol on the state of structural elements of the knee joint

Authors

DOI:

https://doi.org/10.15674/0030-59872013228-33

Keywords:

low-temperatures, ethanol, knee joint, structural changes

Abstract

Morphological changes in the knee joint elements of laboratory rats after exposure to low temperatures and ethanol were studied. It was found out that an injection of ethanol, precooled down to .114 o„R, .50 o„R, .35 o„R, into the joint cavity resulted in damages of the articular cartilage, articular capsule, menisci and subchondral bone depending upon the temperature range. Significant destructive changes were registered in cases of ethanol cooling down to temperatures of .114 and .50 o„R.

References

  1. Malyshkina S. V. Structural and metabolic changes of joint cartilage after local cryoeffect: thesis of biological sciences candidate: 03.00.22 / Malyshkina Svetlana Vladimirovna. — Kharkov, 1985. — 187 р.
  2. General ethical principles of the experiments in animals: proc. of the 3rd National Congress in Bioethics (proceedings of the reports). — Kiev: National Academy of Sciences of Ukraine, 2007. — 16 p.
  3. Bases of histology and histological technique / Ed. by V. G. Eliseyev. — Мoscow: Meditsyna. — 1967. — 286 p.
  4. Patent 56629 Ukraine, IPC G09B 23/28. Method of modeling destructive and dystrophic process in knee joint / Vvedenskiy B. P., Galchenko S. Ye., Kovalov G. О., Synchykova О. P., Sandomirskiy B. P. — Applied. 07.06.10. — Publ. 25.01. 11; Bul. № 2.
  5. Alcohol-facilitated ankylosis of the distal intertarsal and tar¬sometatarsal joints in horses with osteoarthritis / J. Carmalt, C. Bell, L. Panizzi et al. // J. Am. Vet. Med. Assoc. — 2012. — Vol. 240, № 2. — P. 199–204.
  6. Cartilage damage pattern in relation to subchondral plate thickness in a collagenase-induced model of osteoarthritis / S. M. Botter, G. J. van Osch, J. H. Waarsing et al. // Osteoar¬thritis Cartilage. — 2008. — Vol. 16, № 4. — P. 506–514.
  7. Felson D. T. Arthroscopy as a treatment for knee osteoarthritis / D. T. Felson // Best Pract. Res. Clin. Rheumatol. — 2010. — Vol. 24, № 1. — P. 47–50.
  8. Kawaguchi H. Mechanism underlying osteoarthritis induced by mechanical stress on joint cartilage / H. Kawaguchi // Clin. Calcium. — 2008. — Vol. 18, № 9. — P. 1274–1286.
  9. Prevention of cartilage degeneration in a rat model of osteoar¬thritis by intraarticular treatment with recombinant lubricin / C. Flannery, R. Zollner, C. Corcoran et al. // Arthritis Rheum. — 2009. — Vol. 60, № 3. — P. 840–847.
  10. Prognosis of limitations in activities in osteoarthritis of the hip or knee: a 3-year cohort study / G. van Dijk, C. Veenhof, P. Spreeuwenberg et al. // Arch. Phys. Med. Rehabil. — 2010. — Vol. 91, № 1. — P. 58–66.
  11. Use of ethanol in the treatment of distal tarsal joint osteoarthri¬tis: 24cases / L. Lamas, J. Edmonds, W. Hodge et al. // Equine Veterinary Journal. — 2012. — № 44. — P. 399–403.
  12. Use of intra-articular administration of ethyl alcohol for arthrodesis of the tarsometatarsal joint in healthy horses / R. W. Shoemaker, A. L. Allen, C. E. Richardson et al. // Am. J. Vet. Res. — 2006. — Vol. 67, № 5. — P. 850–857.
  13. Valdes A. M. The genetic epidemiology of osteoarthritis / A. M. Valdes, T. D. Spector // Curr. Opin. Rheumatol. — 2010. — Vol. 22, № 2. — P. 139–142.

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How to Cite

Vvedenskiy, B., Dedukh, N., Kovalev, G., & Sandomirskiy, B. (2013). Influence of low temperatures and ethanol on the state of structural elements of the knee joint. ORTHOPAEDICS TRAUMATOLOGY and PROSTHETICS, (2), 28–33. https://doi.org/10.15674/0030-59872013228-33

Issue

No. 2 (2013)

Section

ORIGINAL ARTICLES

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Copyright (c) 2014 Boris Vvedenskiy, Ninel Diedukh, Gennadiy Kovalev, Boris Sandomirskiy

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